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ichijiku enema� was first formulated by Dr. Hatasaburo Tamura in 1925 when he was practicing medicine in Hirakawa-Bashi, Tokyo. Meanwhile, constipation was a major cause of various pediatric illnesses such as fever, cramps, etc. As Dr. Tamura worked round the clock administering urgent care to his patients, he would inject 50% glycerin in an aqueous solution as an enema with a round syringe. In the hopes of alleviating more children of their distress, Dr. Tamura developed ichijiku Brand Light Enema, later known as ichijiku enema�, after 8 years of research. Initially the enemas were sold in celluloid containers, but from 1953 until now, polyethylene containers with almost the same design as the original have been used instead.
